The following players, should they choose to accept LPGA Tour status, would become 2022 LPGA Tour rookies:
2021 EPSON TOUR GRADUATES (4)
Casey Danielson (United States), Sophia Schubert (United States), Amanda Doherty (United States), Morgane Metraux (Switzerland)
LPGA Q-SERIES TOP-45 AND TIES (28)
Na Rin An (Republic of Korea), Hye-Jin Choi (Republic of Korea), Allisen Corpuz (United States), Olivia Cowan (Germany), Karis Davidson (Australia), Ayaka Furue (Japan), Linn Grant (Sweden), Haylee Harford (United States), Lauren Hartlage (United States), Yaeeun Hong (Republic of Korea), Yu-Chiang Hou (Chinese Taipei), Yu-Sang Hou (Chinese Taipei), Gina Kim (United States), Stephanie Kyriacou (Australia), Agathe Laisne (France), Brooke Matthews (United States), Sanna Nuutinen (Finland), Kaitlyn Papp (United States), Jessica Peng (Chinese Taipei), Pauline Roussin-Bouchard (France), Hinako Shibuno (Japan), Maddie Szeryk (Canada), Atthaya Thitikul (Thailand), Savannah Vilaubi (United States), Dewi Weber (Netherlands), Ruoning Yin (China), Katie Yoo (United States), Weiwei Zhang (China)